Resorcinol 108-46-3 manufacturer

The synthetic methods

1. There are many preparation methods of resorcinol, such as benzene sulfonation alkali fusion method, resorcinol and phenol co-production method, resorcinediamine method, m-diisopropyl benzene method, m-aminophenol hydrolysis method, etc. Benzene sulfonation alkali fusion method takes benzene as raw material, by sulfonation to m-benzene disulfonic acid, and then by neutralization alkali fusion, acidification and obtained. The sulfonates were obtained by adding benzene, 65% fuming sulfuric acid and sodium sulfate into the reactor at 75℃. Then add anhydrous sodium sulfate to the sulfonate, stir and heat to 175℃ to dissolve it, add sulfur trioxide at this temperature, and then react for 1.5h, to obtain disulfonate (benzene disulfonate content 75%). The sulfonated compound was neutralized with dilute alkali solution, and the excess sulfate was removed, and the resulting sodium benzenesulfonate was gradually added to the melted sodium hydroxide at 290℃, which was heated to 325℃ in 15min. Then, the alkali melt was dissolved in water, acidified with sulfuric acid, extracted with ethyl ether, and the finished resorcinol was evaporated.

2. This product can be obtained after alkali melting and acidification of potassium m-benzene disulfonate.

The operation procedure was as follows: benzene, 60% fuming sulfuric acid and sodium sulfate were added into the reaction pot, the reaction temperature was controlled at 75℃, and the sulfonate obtained contained 75% benzenesulfonic acid, 1% diphenyl sulfone, 20% sulfuric acid and 4% sodium sulfate. Then add anhydrous sodium sulfate, stir and heat to 175℃, add sulfur trioxide and react for 1.5h, the product is composed of 75% benzene disulfonic acid, diphenyl sulfone disulfonic acid 4%, sulfuric acid 17%, sodium sulfate 4%. After being neutralized by dilute alkali and removing excess sulfate, the sodium benzdisulfonate was obtained, which was added into the molten sodium hydroxide at 290℃ and heated to 325℃ within 15min. The alkali solution was dissolved in water, acidified with sulfuric acid, and then extracted with ethyl ether or butanol. After the solvent was recovered by distillation of the extraction liquid, the crude product was obtained. The crude product was distilled under pressure, and the distillate was collected at 178℃ to form resorcinol.

3. M-diisopropyl benzene oxidation method (HOP method) : m-diisopropyl benzene oxidation method is similar to the oxidation of isopropyl benzene to phenol and acetone method. Benzene with propylene alkylation reaction between generated under the catalyst diisopropyl benzene, diisopropyl benzene in between 80 ~ 90 ℃, the weak alkaline condition bubbled into oxygen and air oxidation reaction generated between two hydrogen peroxide diisopropyl benzene and by-products diisopropyl benzene hydroxyl peroxide, between the crystallization, filtration separation between out two hydrogen peroxide diisopropyl benzene, again under the condition of 80 ℃ with sulfuric acid or phosphoric acid dissociation between benzodiazepines and acetone. With the increasingly strict requirements of environmental protection, this method will be the development direction of resorcinol synthesis in industry.

The storage method

Precautions for storage: Store in a cool, ventilated warehouse. Keep away from fire and heat. The storage temperature should not exceed 35℃, and the relative humidity should not exceed 80%. The packing should be sealed and not in contact with air. It should be stored separately from oxidizing agents, acids, alkalids and edible chemicals, and should not be mixed. Equip with the corresponding variety and quantity of fire fighting equipment. The storage area shall be provided with suitable materials to hold the leakage.

use

1. Resorcinol is mainly used for rubber adhesives, synthetic resins, dyes, preservatives, medicine and analytical reagent, such as primary side, resorcinol and phenol, cresol are similar, and formaldehyde condensation polymer, can be used in making viscose rayon and nylon tyre cord adhesive, preparation of cement, wood glue used for vinyl material and metal, resorcinol is many azo dye, fur dyes intermediates, raw materials and pharmaceutical intermediates for nitrogen base salicylic acid. Rescinol has a bactericidal effect, can be used as a preservative, added in cosmetics and skin disease medicine paste and ointment. The derivative of resorcinol, β-methyl umbelliferone, is the intermediate of optical bleaching agent, trinitroresorcinone is the detonator detonator, and a considerable amount of resorcinone is used in the production of benzophenone ultraviolet absorbers. This product can irritate the skin and mucous membrane, can be quickly absorbed through the skin to cause poisoning disease. The minimum lethal dose of subcutaneous injection in rats was 450mg/kg.

2. Used for the determination of nitrite and nitrate. Zinc, lead, furaldehyde, sugar and ketone can be detected by colorimetric method in the presence of ammonia. Also used in organic synthesis, pharmaceutical industry.

3. Used as accelerator for curing epoxy resin and ultraviolet absorber for synthetic resin, adhesives, dyes and medicine (p aminosalicylic acid). Also used in the synthesis of resorcinol formaldehyde resin adhesives. Resorcinol is an important organic chemical product and intermediates, in tires, rubber hoses and adhesive tape, use of resorcinol  formaldehyde (RF) resin impregnation tree rayon and polyamide fibre cord, can increase between the tyre and rubber adhesive. With resorcinol  cyanuric acid three aryl ester  formaldehyde resin processing steel wire cord, can improve the bonding performance of steel wire for rubber. By adding resorcinol, hexamethylenetetramine and silica into rubber compound, the reinforcing effect of short fiber in rubber matrix can be improved. Bis (diphenylphosphonic acid) resorcinol ester synthesized from resorcinol is a kind of non-halogen flame retardant with high thermal stability, which is suitable for modified polyether, polycarbonate, ABS resin and various thermoplastic resins and polyurethane plastics. Resorcinol also has a certain bactericidal effect.

4. Used as a variety of organic medicine and dye manufacturing, is the intermediate of fur dyes. It is used in medicine to treat eczema, psoriasis and other skin diseases. In the cosmetic industry, used in hair dye formulations (as complex dyes). Rescinol has a bactericidal effect and can be used as a preservative. It is added to pasts and ointments of cosmetics and skin medicines.

5. Used in medicine, dyestuff, rubber, plastic, photographic materials, chemical fiber, explosive industry, such as synthetic amino salicylic acid, dye start red, diphenyl ketone uv absorber, etc., are also used in the preparation of tire cord resin, urea formaldehyde resin foam foaming agent solution, and prevent acne cosmetics additive drugs, regrowth of fungicide, etc.

6. Used for making dyestuff, plastic, medicine, synthetic fiber, etc.