4-Methoxyphenol 150-76-5 manufacturer
4-Methoxyphenol 150-76-5 price
4-Methoxyphenol 150-76-5 in stock
Physicochemical properties
White crystal appearance
Application: it is mainly used as polymerization inhibitor of vinyl monomer, UV inhibitor, dye intermediate and BHA synthesis of edible oil and cosmetics antioxidant
Synonyms:Eastman HQMME;ethermonomethyliqued’hydroquinone;Hqmme;Hydroquinone methyl ether;hydroquinonemethylether;Leucobasal;Leucodine b;leucodineb
CAS:150-76-5
MF:C7H8O2
MW:124.14
EINECS:205-769-8
Product Categories:Liquid Crystal intermediates;Phenol&Thiophenol&Mercaptan;API intermediates;Biochemistry;Building Blocks for Liquid Crystals;Functional Materials;Phenols (Building Blocks for Liquid Crystals);Reagents for Oligosaccharide Synthesis;Aromatic Ethers;organic synthesis;Aromatics;Building Blocks;C6 to C8;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Phenols
4-Methoxyphenol Chemical Properties
Melting point：56 °C
Boiling point：243 °C(lit.)
density：1,55 g/cm3
vapor density：4.3 (vs air)
vapor pressure：<0.01 mm Hg ( 20 °C)
refractive index：1.5286 (estimate)
Fp：>230 °F
storage temp. Refrigerator
solubility Soluble in acetone, ethyl acetate, ethanol, ether, benzene and carbon tetrachloride.
pka10.21(at 25℃)
form：Liquid
color：Clear colorless to pale yellow
PH：5.1 (30g/l, H2O, 20℃)
Odor Threshold0.0027ppm
Water Solubility 40 g/L (25 oC)
BRN 507924
Stability:Stable. Combustible. Incompatible with halogens, oxidizing agents.
InChIKey：NWVVVBRKAWDGAB-UHFFFAOYSA-N
CAS DataBase Reference：150-76-5(CAS DataBase Reference)
NIST Chemistry Reference：Mequinol(150-76-5)
EPA Substance Registry Systemp-Methoxyphenol (150-76-5)
Safety Information
Hazard Codes：Xn
Risk Statements：22-36-43
Safety Statements：24/25-26-37/39-46
WGK Germany：1
RTECS SL7700000
Autoignition Temperature：789 °F
TSCA：Yes
HS Code：29095090
Hazardous Substances Data：150-76-5(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: 1600 mg/kg
4-Methoxyphenol Usage And Synthesis
Chemical Properties：White crystals.
Chemical Properties：4-Methoxyphenol is a colorless to white, waxy solid with an odor of caramel and phenol. A combustible solid.
Uses：Intermediates of Liquid Crystals
Uses：Inhibitor for acrylic monomers; stabilizer for chlorinated hydrocarbons and ethyl cellulose; UV inhibitor
Uses：5HT1&2 receptor antagonist.
Mequinol (4-hydroxyanisole) is a substrate of the enzyme tyrosinase and acts as a competitive inhibitor of melanogenesis.
Indications：Mequinol (4-hydroxyanisole) is a substrate of the enzyme tyrosinase and acts as a competitive inhibitor of melanogenesis.
Synthesis Reference(s)The Journal of Organic Chemistry, 42, p. 1479, 1977 DOI: 10.1021/jo00428a054
Synthesis, p. 751, 1983
Tetrahedron Letters, 34, p. 7667, 1993
General Description：Pink crystals or white waxy solid.
Air & Water Reactions：Sensitive to moisture. Water soluble.
Reactivity Profile：4-Methoxyphenol can react with oxidizing materials.
Hazard：Eye irritant and skin damage.
Health Hazard：4-Methoxyphenol is expected to cause liver and renal toxicity with narcosis, but only at high levels of exposure.
Fire Hazard：Combustible
Safety Profile：Poison by intraperitoneal route. A skin irritant. When heated to decomposition it emits acrid smoke and fumes. See also ETHERS.
ShippingUN3335 Aviation regulated solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.
Purification Methods：Crystallise 4-methoxyphenol from *benzene, pet ether or H2O, and dry it under vacuum over P2O5 at room temperature. Sublime it in vacuo. [Wolfenden et al. J Am Chem Soc 109 463 1987, Beilstein 6 IV 5717.]
