Products Details

Appearance & Physical State
It is the main industrial bactericide, antiseptic and enzyme inhibitor. It is the main industrial bactericide, antiseptic and enzyme inhibitor
Widely used in latex products, water-soluble resin, paint (latex paint), acrylic acid, polymer. Polyammonium products, photographic lotion, paper, ink, leather, lubricating oil and other products
Synonyms:Benzisothiazolin-3-on (BIT);Benzo[d]isothiazol-3(2H)-one;1,2-Benzisothiazolin-3-One(MIT);2$l^{4}-thia-6-azatricyclo[5.4.0.0^{2,6}]undeca-1(7),8,10-trien-5-one;1,2-benzo-isothiazolin-3-ketone;Acticide BIT;Apizas AP-DS;Bestcide 200K
CAS:2634-33-5
MF:C7H5NOS
MW:151.19
EINECS:220-120-9
Product Categories:BA - BH;Beverage Standards;DIN and DL 152;European Community: ISO;Method Specific;Preservatives &;A-B;Alpha Sort;Alphabetic;Analytical Standards;Analytical/Chromatography;Antioxidants;Building Blocks;C3 to C7;Chemical Synthesis;Chromatography;Environmental Standards;Food &;Heterocyclic Building Blocks;Volatiles/ Semivolatiles;Preservative;Heterocyclic Building Blocks;Thiazoles;76/768/EEC;BA - BHChromatography;Preservatives&AntioxidantsBuilding Blocks;ThiazolesMethod Specific;A-BAlphabetic;Alpha Sort;B;European Community: ISO and DIN;Food&Beverage Standards;Sulphur Derivatives;Heterocycles;Hydantoins & Derivatives;Intermediates & Fine Chemicals;Pharmaceuticals;Building Blocks;Aromatics;Sulfur & Selenium Compounds;Industrial/Fine Chemicals;chemical;Volatiles/ Semivolatiles
1,2-Benzisothiazol-3(2H)-one Chemical Properties
Melting point 154-158 °C(lit.)
Boiling point 360°C (rough estimate)
density 1.2170 (rough estimate)
refractive index 1.5500 (estimate)
storage temp. -20°C Freezer
solubility Soluble in dichloromethane, dimethyl sulfoxide, methanol.
pka10.19±0.20(Predicted)
form neat
InChIKeyDMSMPAJRVJJAGA-UHFFFAOYSA-N
CAS DataBase Reference2634-33-5
EPA Substance Registry System1,2-Benzisothiazolin-3-one (2634-33-5)
Safety Information
Hazard Codes Xn,N
Risk Statements 22-38-41-43-50
Safety Statements 24-26-37/39-61
RIDADR UN 3077 9/PG 3
WGK Germany 2
RTECS DE4620000
HazardClass 9
HazardClass IRRITANT
PackingGroup Ⅲ
HS Code 29339900
ToxicityLD50 oral in rat: 1020mg/kg
1,2-Benzisothiazol-3(2H)-one Usage And Synthesis
DescriptionBIT is an irritant and also a skin sensitizer. Occupational allergie contact dermatitis has been reported mainly related to the use of cutting oils and greases in paint manufacturers, pottery mouldmakers, acrylic emulsion manufacturers, plumbers, printers and lithoprinters, paper makers, an analyticallaboratory, a rubber factory, and in employees manufacturing air fresheners.
Chemical PropertiesYellow Powder
UsesAntimicrobial agent.
UsesIsothiazolinone BIT is widely used in industry as a preservative in water-based solutions, such as pastes, paints and cutting oils. It exists at different concentrations in the different Proxel AB, GXL, CRL, XL2, XL, HL, TN, and in Mergal K-10.
Usespreservative in cooling fluids, paints, adhesives paper and in the textile industry
DefinitionChEBI: An organic heterobicyclic compound based on a fused 1,2-thiazole and benzene bicyclic ring skeleton, with the S atom positioned adjacent to one of the positions of ring fusion.
Contact allergensBIT, both an irritant and a skin sensitizer, is widely used in industry as a preservative in water-based solutions such as pastes, paints, and cutting oils. Occupational dermatitis has been reported mainly due to cutting fluids and greases, in paint manufacturers, pottery moldmakers, acrylic emulsions manufacturers, plumber,printers and lithoprinters, paper makers, analytical laboratory, rubber factory, and employees manufacturing air fresheners. It is also a preservative in vinyl gloves.
Safety ProfileModerately toxic by ingestion.When heated to decomposition it emits toxic vapors ofNOx and SOx.
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