R-alpha-Lipoic Acid CAS 1200-22-2_
English Deutsch Spanish Japanese Korean
  Home  About chemwill  Product Core Technology R&D and Manufactory Specialised field QA & QC Inquiry Contact  
  Advanced intermediate  
  Drug intermediate  
                     Active Ingredient
  APIs & Nutraceutical  
  Animal health  
  Natural ingredient  
                     Optic & Electronic Materials
  OLED & LCD  
  Photoresist chemical  
  IT-related chemicals  
  Other Eletronic Chemicals  
                     Functional group categories
  Fluorine chemical  
  Boronic acid  
  Indole/ Isatin  
  Naphthalene/ Anthracene  
  Halogenated compound  
  Heterocyclic compound  
                     Other chemicals
  Metal Catalyst  
  Battery & Eco-energy  
  Dye & pigment  
  Flavor & cosmetic  
  Other specialty chemicals  
  Tel: +86-21-5108-6038
Fax: +86-21-5186-1608
E-mail: sales@chemwill.com
R-alpha-Lipoic Acid CAS 1200-22-2
R-alpha-Lipoic Acid CAS 1200-22-2 R-Alpha lipoic acid, also known as dextran lipoic acid, is a white or pale yellow, odorless powdered or crystalline material, common in vitamins and drugs for treatment of chronic hepatitis, psoriasis, lupus erythematosus Appearance: white or yellowish, tasteless powder like / crystalline substance. Optical rotation: +104 degree (c=0.88, benzene, 23) Solubility: insoluble in water, soluble in benzene alcohol, chloroform, lipids. Packing: 5kg/25kg carton packing, lined with polyethylene bags and kraft paper bags. Storage: sealed shading, stored in low-temperature (<30) dry, cool, well ventilated place Vitamins and drugs for acute and chronic hepatitis, cirrhosis of the liver, hepatic coma, fatty liver, diabetes, human acquired immune insufficiency with the original, AIDS, psoriasis, eczema, burns, skin cancer, multiple sclerosis, Parkinson's disease, neurology of disease, rheumatism, rheumatoid arthritis, erythema lupus, scleroderma, autoimmune disease, cataracts, and other eye diseases, heart disease, stroke, atherosclerosis, for acute and chronic hepatitis, cirrhosis of the liver, hepatic coma, fatty liver and other diseases treatment and health care efficacy. At present, its dietary supplement products are powder, mixture, tablet, hard colloid capsule, soft colloid capsule, can also be used in beverage, candy, bread, milk and other functional food. In order to better to make different kinds of diet supplement products and better will ala application in the manufacturing of different types of functional food must placed more than 40 DEG C obstacle stored in a light (UV) to save There are a lot of methods for chemical synthesis of R- in the world, and there are mainly three methods.: 1, to 6, 8-dichloro octanoic acid ethyl ester as starting material, the thio, cyclization, hydrolysis, racemic alpha - lipoic acid (U.S.27924061957 U.S.32237121965), and then split the splitting agent get R-Alpha lipoic acid, yield of this step is only 45%. And S- acid is not easy to R.S type or R type, half of the resources and make R- sulfur acid expensive. 2, 6, 8 dihydroxy methyl caprylate or 6 - 6-hydroxy-8-chlorine octanoic acid methyl ester as the starting material, mesylate made and stereo selectivity into R - lipoic acid (U.S.5869713, G.Bringmann, J.Paust Z.Naturforschung 54B, 661-6651999), but the technology is complex and not easy to get the pure product. 3, the racemic 6, 8-dichloro octanoic acid ethyl ester hydrolysis (+) dichloro acid (DCA), (-) - ephedrine salt, split, thio, cyclization (Acker, J.Am.Chem.Soc., 7664831954), the basic can save cost, but there are still about 50% s - (-) - 6, 8-dichloro octanoic acid did not use, high cost. There is no S- (-) -6, 8- two -6 (+) R-, 8- two, a detailed literature report on the acid and R-
Copyright(C)2013 Chemwill Asia co.,Ltd All Rights Reserved. Sitemap